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Spero Therapeutics Inc.

1.22

+0.02001.67%

Post-market: 1.220.0040+0.33%19:30 EDT

Volume:338.47K

Turnover:411.23K

Market Cap:71.05M

PE:9.55

High:1.23

Open:1.20

Low:1.20

Close:1.20

52wk High:3.08

52wk Low:1.08

Shares:58.23M

Float Shares:45.59M

Volume Ratio:0.84

T/O Rate:0.74%

Dividend:- -

Dividend Rate:- -

EPS(TTM):0.1278

EPS(LYR):0.1500

ROE:19.17%

ROA:7.19%

PB:1.61

PE(LYR):8.13

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Overview Company News Filings

Spero Therapeutics Announces $105 Million Non-recourse Non-dilutive Financing Backed by a Portion of Utebzi Milestones & Royalties

THOMSON REUTERS

Spero Therapeutics - Hcrx to Receive Quarterly Principal and Interest Payments Derived from the GSK Payments Due to Spero Until Loan Repaid

THOMSON REUTERS

Innovent Biologics Licenses Anti-cd40l Antibody Ibi355 to Spero in Deal Worth About USD 1.1 Billion

Spero Therapeutics - Innovent to Receive Payments Totaling About $1.1 Bln Plus Tiered Royalties

THOMSON REUTERS

Spero Therapeutics - Innovent to Initiate Phase 2 Trial for Sjögren’s Disease in China by Early 2027

THOMSON REUTERS

Spero Therapeutics - to Initiate Phase 2 Trial for SP001 in Igg4-rd in Q2 2027

THOMSON REUTERS

Innovent Biologics - Spero Receives Exclusive Global Rights to Ibi355 Excluding Greater China

THOMSON REUTERS

Innovent Biologics and Spero Therapeutics Announce Exclusive License for Ibi355 (sp001), a Phase 2-ready Third-generation Anti-cd40l Antibody

THOMSON REUTERS

Avacta Appoints Healthcare Executive Patrick Vink as Deputy Chairman of the Board of Directors

Spero Therapeutics Shareholders Approved Increase in Authorized Common Shares to 240 Million

Spero Therapeutics says FDA approves Utebzi oral antibiotic for complicated UTIs in adults

GSK, Spero Therapeutics Get FDA Approval for Utebzi in Complicated Urinary Tract Infections

MT Newswires Live

GSK Says cUTI Oral Antibiotic Tebipenem Approved By US FDA

GSK, Spero Therapeutics announce FDA approval of Utebzi

US FDA approves GSK's oral antibiotic for drug-resistant UTIs

BRIEF-FDA Approves First Oral Carbapenem Therapy For Complicated Urinary Tract Infections

GSK - Tebipenem Pivoxil Expected to Be Available in US by End of 2026

THOMSON REUTERS

Promising Penny Stocks To Consider In May 2026

Simply Wall St.

Spero Therapeutics Q1 revenue drops on decreased clinical activity

Spero Therapeutics Q1 Operating Expenses USD 7.796 Million

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Ibi355 Excluding Greater China","url":"https://stock-news.laohu8.com/highlight/detail?id=2651171906","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2651171906?lang=en_us&edition=fundamental","pubTime":"2026-07-14 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tumor-activate","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2026/07/08/3323819/0/en/Avacta-Appoints-Healthcare-Executive-Patrick-Vink-as-Deputy-Chairman-of-the-Board-of-Directors.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"executive","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["PATK","ACHFF","PDC","BK4581","BK4137","HCSG","LU0128526141.USD","XBI","BK4123","LU0029874061.USD","BK4585","XLV","BK4124","BK4121","BK4588","BK4139","SPRO","LABU"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2646389327","title":"Spero Therapeutics Shareholders Approved Increase in Authorized Common Shares to 240 Million","url":"https://stock-news.laohu8.com/highlight/detail?id=2646389327","media":"Reuters","labels":["executive","shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2646389327?lang=en_us&edition=fundamental","pubTime":"2026-06-26 05:09","pubTimestamp":1782421760,"startTime":"0","endTime":"0","summary":"Spero Therapeutics shareholders approved increase in authorized common shares to 240 millionSpero Therapeutics held its annual shareholder meeting on June 23, 2026.Shareholders ratified Pricewaterhous","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260625:nNDL9zjNCg:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"executive,shareholding","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","SPRO"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2645077172","title":"Spero Therapeutics says FDA approves Utebzi oral antibiotic for complicated UTIs in adults","url":"https://stock-news.laohu8.com/highlight/detail?id=2645077172","media":"Reuters","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2645077172?lang=en_us&edition=fundamental","pubTime":"2026-06-23 04:06","pubTimestamp":1782158760,"startTime":"0","endTime":"0","summary":"FDA cleared Utebzi  for adults with complicated UTIs, including pyelonephritis, with limited or no alternative oral options.GSK holds exclusive global rights under a licensing deal with Spero Therapeutics, excluding select Asian territories.Decision based on Phase III PIVOT-PO data showing non-inferiority versus IV imipenem-cilastatin; overall response 58.5% vs 60.2%.Launch targeted by end-2026, positioning Utebzi as the first oral carbapenem available in the US.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Spero Therapeutics Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on June 22,","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260622:nNDLGvvsr:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SPRO","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2644740373","title":"GSK, Spero Therapeutics Get FDA Approval for Utebzi in Complicated Urinary Tract Infections","url":"https://stock-news.laohu8.com/highlight/detail?id=2644740373","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2644740373?lang=en_us&edition=fundamental","pubTime":"2026-06-18 00:00","pubTimestamp":1781712056,"startTime":"0","endTime":"0","summary":"GSK  and Spero Therapeutics  said Wednesday that the US Food and Drug Administration has approved Utebzi as treatment for complicated urinary tract infections, including pyelonephritis, in adults.Utebzi, or tebipenem pivoxil, is the first and only oral carbapenem antibiotic approved in the US and is expected to become available by the end of 2026, the companies said.The approval was based on phase 3 trial data showing Utebzi's non-inferiority to intravenous imipenem-cilastatin, with tebipenem pivoxil achieving an overall success rate of 58.5% against 60.2% for imipenem-cilastatin, according to a statement. Tebipenem pivoxil's safety profile is also \"generally similar\" to that of imipenem-cilastatin, the companies said.GSK shares were up about 1%, while Spero stock was down more than 14% in Wednesday trading.Price: 52.72, Change: +0.50, Percent Change: +0.96","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["LU1829250122.USD","BK4539","GSK.UK","BK4588","LENZ","BK4007","BK4585","BK4139","GSK","GSKH","LABU","BK4532","SPRO"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2644471547","title":"GSK Says cUTI Oral Antibiotic Tebipenem Approved By US FDA","url":"https://stock-news.laohu8.com/highlight/detail?id=2644471547","media":"Reuters","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2644471547?lang=en_us&edition=fundamental","pubTime":"2026-06-17 23:26","pubTimestamp":1781710006,"startTime":"0","endTime":"0","summary":"June 17 (Reuters) - GSK plc ::*GSK PLC  - CUTI ORAL ANTIBIOTIC TEBIPENEM APPROVED BY US FDA*GSK - TEBIPENEM PIVOXIL EXPECTED TO BE AVAILABLE IN US BY END OF 2026  ((Reuters Investor Briefs; email: reutersinvestor.briefs@thomsonreuters.com))  Source Date/Time = 17-JUN-202615:06:03 GMT","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260617:nRSD18MCjB:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","SPRO"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2644674796","title":"GSK, Spero Therapeutics announce FDA approval of Utebzi","url":"https://stock-news.laohu8.com/highlight/detail?id=2644674796","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2644674796?lang=en_us&edition=fundamental","pubTime":"2026-06-17 23:17","pubTimestamp":1781709438,"startTime":"0","endTime":"0","summary":"GSK plc (GSK) and Spero Therapeutics (SPRO) announced that the Food and Drug Administration has approved Utebzi, an oral antibiotic for the treatme...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/gsk-spero-therapeutics-announce-fda-approval-of-utebzi-thefly-news-2?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/gsk-spero-therapeutics-announce-fda-approval-of-utebzi-thefly-news-2?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["GSK.UK","BK4585","GSKH","BK4007","BK4539","LABU","LENZ","SPRO","LU1829250122.USD","BK4139","BK4532","BK4588","GSK"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2644747895","title":"US FDA approves GSK's oral antibiotic for drug-resistant UTIs","url":"https://stock-news.laohu8.com/highlight/detail?id=2644747895","media":"Reuters","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2644747895?lang=en_us&edition=fundamental","pubTime":"2026-06-17 23:08","pubTimestamp":1781708936,"startTime":"0","endTime":"0","summary":"US FDA approves GSK's oral antibiotic for drug-resistant UTIsJune 17  - The U.S. FDA has approved GSK's GSK.L oral antibiotic to treat complicated urinary tract infections, the regulator said on Wednesday, giving patients a new treatment option against drug-resistant infections.   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FDA:FDA APPROVES FIRST ORAL CARBAPENEM THERAPY FOR COMPLICATED URINARY TRACT INFECTIONSFDA: APPROVED UTEBZI  TABLETS FOR THE TREATMENT OF COMPLICATED URINARY TRACT INFECTIONS ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260617:nFWN42P0CE:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU1983299246.USD","LU0306807586.USD","LU0557290698.USD","LU0203347892.USD","LU0225283273.USD","LU1400636491.USD","LU0971552830.HKD","LU1228905540.USD","SGXZ57979304.SGD","LU0985481810.HKD","SG9999001176.USD","GSK.UK","LU0161305163.EUR","LU1670756490.USD","IE0034235071.USD","LU0545562505.USD","LU1202635105.USD","LU1309081286.SGD","BK5011","LU0203345920.USD","LU0058720904.USD","LU0211331839.USD","LU0321505439.SGD","LU0321505868.SGD","LU1302929846.USD","LU2646069778.SGD","LU1487256676.USD","LU1481599808.USD","LU1400636574.HKD","LU0225284248.USD","LU1015430645.USD","IE00B3T34201.USD","IE00BQJZX424.USD","LU0971552673.USD","LU1064927863.SGD","IE00BWDBJ516.SGD","LU1400636657.SGD","SG9999013999.USD","LU0306806265.USD","SG9999001176.SGD","LU0289739699.SGD","LU1098665638.USD","BK4139","LU0575583348.USD","LU1645745479.HKD","SPRO","LU0225771236.USD","LU0109981661.USD","LU0987226296.USD","LU1035777561.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2644574785","title":"GSK - Tebipenem Pivoxil Expected to Be Available in US by End of 2026","url":"https://stock-news.laohu8.com/highlight/detail?id=2644574785","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2644574785?lang=en_us&edition=fundamental","pubTime":"2026-06-17 23:06","pubTimestamp":1781708763,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260617:nTUC4JKXRB:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["LU1046248800.SGD","LU1481600234.SGD","BK5011","LU0306807586.USD","IE00B3T34201.USD","SG9999013999.USD","LU0557290698.USD","LU1228905540.USD","LU1487256676.USD","LU1400636491.USD","LU1098665638.USD","GSK.UK","LU1400636574.HKD","LU2646069778.SGD","LU1400636657.SGD","LU2468319806.SGD","SG9999001176.SGD","LU1064927863.SGD","LU0225284248.USD","LU1015430645.USD","LU1302929846.USD","LU0321505868.SGD","LU0321505439.SGD","IE0034235071.USD","LU0545562505.USD","IE00BQJZX424.USD","LU0203347892.USD","LU1228905037.USD","SPRO","LU0575583348.USD","LU0109981661.USD","LU1035777561.USD","LU0987226296.USD","LU0985481810.HKD","LU0225283273.USD","SGXZ57979304.SGD","LU2089984988.USD","LU0289739699.SGD","LU1309081286.SGD","LU1202635105.USD","LU1481599808.USD","LU0058720904.USD","LU1645745479.HKD","LU1983299246.USD","IE00BWDBJ516.SGD","LU1670756490.USD","LU0971552830.HKD","BK4139","LU0161305163.EUR","LU0971552673.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2635896510","title":"Promising Penny Stocks To Consider In May 2026","url":"https://stock-news.laohu8.com/highlight/detail?id=2635896510","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2635896510?lang=en_us&edition=fundamental","pubTime":"2026-05-15 19:05","pubTimestamp":1778843111,"startTime":"0","endTime":"0","summary":"The United States market has shown impressive growth, with a 1.1% increase over the last week and a substantial 27% rise over the past year, alongside expectations for earnings to grow by 17% annually in the coming years. Penny stocks, while an older term, continue to capture attention as they often represent smaller or newer companies that provide growth opportunities at lower price points. 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