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Septerna, Inc.

38.15

-0.7600-1.95%

Volume:415.35K

Turnover:15.86M

Market Cap:1.78B

PE:-70.33

High:39.11

Open:38.71

Low:37.39

Close:38.91

52wk High:51.10

52wk Low:11.98

Shares:46.68M

Float Shares:22.90M

Volume Ratio:1.24

T/O Rate:1.81%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-0.5424

EPS(LYR):-1.1044

ROE:-6.34%

ROA:-7.13%

PB:4.60

PE(LYR):-34.54

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Overview Company News Filings

Press Release: Septerna Highlights Business Progress and Reports Second Quarter 2026 Financial Results

Septerna SVP Drug Discovery Daniel D. Long Sells USD 114,901.29 in Common Shares

3 Small-Cap Stocks Analysts Expect to Rally Big

3 Small-Cap Stocks with ‘Strong Buy’ Ratings and 40%+ Upside, According to Analysts

Septerna President and COO Elizabeth Bhatt Sells 4,000 Shares for $135,974

Is Septerna (SEPN) Fully Valued Following Its Russell Index Inclusions?

Simply Wall St.

Septerna SVP Drug Discovery Daniel D. Long Disposes of 3,333 Common Shares Worth $113,104.20

Truist Securities Adjusts Septerna Price Target to $43 From $35, Maintains Buy Rating

MT Newswires Live

Septerna Price Target Maintained with a $40.00/share by HC Wainwright & Co.

Septerna is Maintained at Buy by Truist Securities

Septerna price target raised to $43 from $35 at Truist

Analysts Offer Insights on Technology Companies: Septerna, Inc. (SEPN) and Strategy (MSTR)

Septerna price target lowered to $45 from $52 at Guggenheim

Septerna Buy Rating Reiterated as Analyst Sees Favorable Risk‑Reward and Keeps $40 Price Target Unchanged

Septerna Chief People Officer Samira Shaikhly Disposes of 2,178 Common Shares for $76,638.24

Septerna Holds Annual Shareholder Meeting

Cantor Fitzgerald Reaffirms Their Buy Rating on Septerna, Inc. (SEPN)

Septerna SVP Drug Discovery Daniel D. Long Disposes of 15,000 Common Shares Worth $548,782

Is Guggenheim’s New Coverage of Septerna (SEPN) Reframing the Story Around Operating Efficiency?

Simply Wall St.

Wells Fargo Keeps Their Buy Rating on Septerna, Inc. (SEPN)

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To fully characterize steady-state. pharmacokinetics, dosing for the MAD cohorts will be extended to. 14 days. As a result, Septerna expects to report Phase 1 data from. both the SAD and MAD cohorts in the first quarter of 2027.-- During the quarter, the Company presented the first detailed. preclinical characterization of SEP-479 in an oral presentation at. ENDO 2026, highlighting data supporting its potential as a. -- As reported in March 2026, SEP-631, an oral small molecule MRGPRX2","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["R","BK4599","BK4022","BK4007","BK4232","SEPN","BK4097","PRGS","LU2065732104.USD","GPCR"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2657572937","title":"Septerna SVP Drug Discovery Daniel D. 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Analysts are highlighting Septerna, Inc. ($SEPN), Kornit Digit...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/3-small-cap-stocks-with-strong-buy-ratings-and-big-upside-according-to-analysts?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/3-small-cap-stocks-with-strong-buy-ratings-and-big-upside-according-to-analysts?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4007","SEPN"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2652337002","title":"Septerna President and COO Elizabeth Bhatt Sells 4,000 Shares for $135,974","url":"https://stock-news.laohu8.com/highlight/detail?id=2652337002","media":"Reuters","labels":["shareholding","insiderTrades"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2652337002?lang=en_us&edition=fundamental","pubTime":"2026-07-18 07:01","pubTimestamp":1784329288,"startTime":"0","endTime":"0","summary":"Septerna President and COO Elizabeth Bhatt sells 4,000 shares for $135,974Septerna President and COO Elizabeth Bhatt sold 4,000 shares on July 15 at USD 33.99.She exercised stock options for 4,000 sha","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260717:nNDL633WXk:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":"Septerna President and COO Elizabeth Bhatt Sells 4,000 Shares for $135,974","news_tag":"shareholding,insiderTrades","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SEPN","BK4007"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2650615176","title":"Is Septerna (SEPN) Fully Valued Following Its Russell Index Inclusions?","url":"https://stock-news.laohu8.com/highlight/detail?id=2650615176","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650615176?lang=en_us&edition=fundamental","pubTime":"2026-07-11 23:28","pubTimestamp":1783783710,"startTime":"0","endTime":"0","summary":"Septerna (SEPN) recently joined several Russell growth and small cap indices. This change can affect how index-tracking and benchmark-aware funds treat the stock and influence overall investor attention.\nSee our latest analysis for Septerna.\nSepterna’s recent Russell index inclusions come after a strong run in the stock, with a 90 day share price return of 55.61% and a 1 year total shareholder return of 206.31%. This comes even though the latest close at $35.93 followed a 1 day share price...","market":"nz","thumbnail":"https://images.simplywall.st/asset/industry/6121000-choice2-main-header/1585186699299","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6121000-choice2-main-header/1585186699299"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-sepn/septerna/news/is-septerna-sepn-fully-valued-following-its-russell-index-in","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-sepn/septerna/news/is-septerna-sepn-fully-valued-following-its-russell-index-in","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["BK4007","SEPN"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2648639940","title":"Septerna SVP Drug Discovery Daniel D. 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Investo...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/septerna-price-target-raised-to-43-from-35-at-truist-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/septerna-price-target-raised-to-43-from-35-at-truist-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["SEPN"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2648517312","title":"Analysts Offer Insights on Technology Companies: Septerna, Inc. 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(SEPN) and Strategy (MSTR) with bulli...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/analysts-offer-insights-on-technology-companies-septerna-inc-sepn-and-strategy-mstr-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/analysts-offer-insights-on-technology-companies-septerna-inc-sepn-and-strategy-mstr-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["MSDD","SMI3.UK","WNTR","3LMI.UK","BK4585","BK4596","MSTW","SMST","MSTK","MTYY","BK4595","BK4023","SEPN","MSTY.UK","MST","MSTY","09799","09399","BK4516","LMI3.UK","BK4007","MSST","IMST","MSOO","MSTZ","3SMI.UK","BK4600","MSII","07799","MSTR","APED","BK4588","MSTP","MSTU","MSTX","07399"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2648517813","title":"Septerna price target lowered to $45 from $52 at Guggenheim","url":"https://stock-news.laohu8.com/highlight/detail?id=2648517813","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2648517813?lang=en_us&edition=fundamental","pubTime":"2026-07-01 18:50","pubTimestamp":1782903037,"startTime":"0","endTime":"0","summary":"Guggenheim analyst Seamus Fernandez lowered the firm’s price target on Septerna (SEPN) to $45 from $52 and keeps a Buy rating on the shares after E...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/septerna-price-target-lowered-to-45-from-52-at-guggenheim-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/septerna-price-target-lowered-to-45-from-52-at-guggenheim-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["SEPN"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2648514452","title":"Septerna Buy Rating Reiterated as Analyst Sees Favorable Risk‑Reward and Keeps $40 Price Target Unchanged","url":"https://stock-news.laohu8.com/highlight/detail?id=2648514452","media":"TIPRANKS","labels":["express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2648514452?lang=en_us&edition=fundamental","pubTime":"2026-07-01 18:15","pubTimestamp":1782900928,"startTime":"0","endTime":"0","summary":"H.C. 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Ram Selvaraju has given his...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/ratings/septerna-buy-rating-reiterated-as-analyst-sees-favorable-riskreward-and-keeps-40-price-target-unchanged-ratings-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate","earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/ratings/septerna-buy-rating-reiterated-as-analyst-sees-favorable-riskreward-and-keeps-40-price-target-unchanged-ratings-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"express","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["SEPN"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2648598606","title":"Septerna Chief People Officer Samira Shaikhly Disposes of 2,178 Common Shares for $76,638.24","url":"https://stock-news.laohu8.com/highlight/detail?id=2648598606","media":"Reuters","labels":["shareholding","insiderTrades"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2648598606?lang=en_us&edition=fundamental","pubTime":"2026-07-01 07:02","pubTimestamp":1782860537,"startTime":"0","endTime":"0","summary":"Septerna Chief People Officer Samira Shaikhly disposes of 2,178 common shares for $76,638.24Septerna Chief People Officer Samira Shaikhly sold 2,178 common shares at USD 35.18 on June 29.Sale followed","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260630:nNDL1hBmNr:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":"Septerna Chief People Officer Samira Shaikhly Disposes of 2,178 Common Shares for $76,638.24","news_tag":"shareholding,insiderTrades","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4007","SEPN"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2648562803","title":"Septerna Holds Annual Shareholder Meeting","url":"https://stock-news.laohu8.com/highlight/detail?id=2648562803","media":"Reuters","labels":["conferences"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2648562803?lang=en_us&edition=fundamental","pubTime":"2026-07-01 04:31","pubTimestamp":1782851514,"startTime":"0","endTime":"0","summary":"Septerna holds annual shareholder meetingSepterna held its annual shareholder meeting on June 26, 2026.Shareholders elected Shalini Sharp and Jake Simson to the board.Shareholders ratified Ernst & You","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260630:nNDL185SHp:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"conferences","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4007","SEPN"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2647537555","title":"Cantor Fitzgerald Reaffirms Their Buy Rating on Septerna, Inc. 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Th...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/cantor-fitzgerald-reaffirms-their-buy-rating-on-septerna-inc-sepn-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/cantor-fitzgerald-reaffirms-their-buy-rating-on-septerna-inc-sepn-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["SEPN"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2646447258","title":"Septerna SVP Drug Discovery Daniel D. Long Disposes of 15,000 Common Shares Worth $548,782","url":"https://stock-news.laohu8.com/highlight/detail?id=2646447258","media":"Reuters","labels":["shareholding","insiderTrades"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2646447258?lang=en_us&edition=fundamental","pubTime":"2026-06-25 07:25","pubTimestamp":1782343502,"startTime":"0","endTime":"0","summary":"Septerna SVP Drug Discovery Daniel D. Long disposes of 15,000 common shares worth $548,782Septerna SVP, Drug Discovery Daniel D. Long cut his stake to 96,412 shares in Form 4 activity dated June 22, 2","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260624:nNDL2Y01NQ:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Septerna SVP Drug Discovery Daniel D. 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(SEPN)","url":"https://stock-news.laohu8.com/highlight/detail?id=2644044710","media":"TIPRANKS","labels":["express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2644044710?lang=en_us&edition=fundamental","pubTime":"2026-06-17 18:37","pubTimestamp":1781692646,"startTime":"0","endTime":"0","summary":"Wells Fargo analyst Derek Archila maintained a Buy rating on Septerna, Inc. today and set a price target of $48.00. According to TipRanks, Archila ...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/wells-fargo-keeps-their-buy-rating-on-septerna-inc-sepn-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate","earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/wells-fargo-keeps-their-buy-rating-on-septerna-inc-sepn-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"express","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["SEPN","PGF"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":5,"pageCount":2,"totalSize":93,"code":"91000000","status":"200"}]}}