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Praxis Precision Medicines, Inc.

350.30

+5.551.61%

Post-market: 350.300.00000.00%17:06 EDT

Volume:380.51K

Turnover:131.24M

Market Cap:9.76B

PE:-27.23

High:351.72

Open:343.00

Low:333.46

Close:344.75

52wk High:392.70

52wk Low:37.19

Shares:27.85M

Float Shares:24.08M

Volume Ratio:1.22

T/O Rate:1.58%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-12.8634

EPS(LYR):-13.4758

ROE:-38.86%

ROA:-25.65%

PB:7.28

PE(LYR):-25.99

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Overview Company News Filings

Guggenheim Sticks to Its Buy Rating for Praxis Precision Medicines (PRAX)

S&P 500 Futures Fall In Premarket Trading; Hewlett Packard Ent, Marvell Technology Lead

Wells Fargo Sticks to Its Hold Rating for Praxis Precision Medicines (PRAX)

Buy Rating Reaffirmed as Higher Relutrigine Pricing Assumptions Offset Vormatrigine Setback; $537 Price Target Maintained

Yazdi Maintains Buy on Praxis, Trims Price Target to $810 as Vormatrigine Outlook Softens but Core Pipeline Thesis Remains Intact

Praxis Precision Medicines Inc : TD Cowen Cuts Target Price to $510 From $554

THOMSON REUTERS

Praxis Precision price target lowered to $1,201 from $1,245 at H.C. Wainwright

Praxis Precision Medicines, Inc. : H.c. Wainwright Cuts Target Price to $1201 From $1245

THOMSON REUTERS

Praxis Precision Med Is Maintained at Buy by BTIG

U.S. RESEARCH ROUNDUP-Edgewise Therapeutics, IBM, Rubrik

Praxis Precision Medicines Inc : Baird Cuts Target Price to $400 From $433

THOMSON REUTERS

Praxis Precision Reassesses Vormatrigine After Mixed POWER1 Data

Praxis Precision Medicines's Seizure Treatment Fails to Meet Trial's Primary Endpoint

Praxis Precision reports POWER1 study misses endpoint, pauses POWER2 enrollment

Praxis says POWER1 trial of vormatrigine in focal seizures misses primary endpoint

Praxis Precision Medicines - Power1 Study Did Not Meet Primary Endpoint in Refractory Focal Onset Seizures

THOMSON REUTERS

Praxis Precision Medicines - Pauses Enrollment in Power2 Study to Reassess Vormatrigine Program

THOMSON REUTERS

Praxis Precision Medicines - Secondary 50% Response Rate Met; Seizure Reduction More Pronounced at 30 Mg Dose

THOMSON REUTERS

Praxis Precision Medicines Provides Vormatrigine Program Update

THOMSON REUTERS

Praxis Precision Medicines - Vormatrigine Well-Tolerated With Adverse Event Discontinuations Below 10%

THOMSON REUTERS

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In early trading, Praxis Precision Medicines Inc.  and Xometry Inc. Cl A  had posted declines, falling 10.5% and 8.5%, respectively.Meanwhile S&P 500 futures were down 0.21%, with futures for the Dow Jones Industrial Average falling 0.47%. The Cboe Volatility Index futures were up 2.61%.In commodities news, Brent crude oil futures were down 1.36%, and gold futures were up 1.14%. 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On June 1, 2026, Praxis Precision Medicines, Inc. reported topline results from its Ph...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/company-announcements/praxis-precision-reassesses-vormatrigine-after-mixed-power1-data?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/company-announcements/praxis-precision-reassesses-vormatrigine-after-mixed-power1-data?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["IE0009355771.USD","IE00B4R5TH58.HKD","LU0889565916.HKD","PRAX","BK4139","LU0320765992.SGD","IE00BJT1NW94.SGD","IE00BJJMRZ35.SGD","IE00BFTCPJ56.SGD","IE00B2B36J28.USD","LU0109394709.USD","IE0002141913.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2640962558","title":"Praxis Precision Medicines's Seizure Treatment Fails to Meet Trial's Primary Endpoint","url":"https://stock-news.laohu8.com/highlight/detail?id=2640962558","media":"Dow Jones","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2640962558?lang=en_us&edition=fundamental","pubTime":"2026-06-02 04:37","pubTimestamp":1780346220,"startTime":"0","endTime":"0","summary":"Praxis Precision Medicines said vormatrigine, a treatment it is developing for certain seizures and epilepsy, did not meet its primary endpoint in a recent trial.The biopharmaceutical company said Monday it is now pausing enrollment in the study to reassess the program and consider modifications.The Phase 2/3 trial evaluated the safety and efficacy of vormatrigine in adults with focal onset seizures who are concurrently taking at least one but no more than three anti-seizure medications. The study's primary endpoint was the percent change in monthly seizure frequency from baseline.However, the study met a secondary measure for a 50% response rate. Additionally, seizure reduction was more pronounced during the second half of the study, when patients received a higher dose, the company said.\"While the results for POWER1 were not what we hoped for, we are encouraged by the signal we saw on the higher dose arm, the low discontinuation rate and solid safety profile,\" Chief Executive Marcio ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":"Praxis Precision Medicines's Seizure Treatment Fails to Meet Trial's Primary Endpoint","news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IE0002141913.USD","IE00B4R5TH58.HKD","IE00BJJMRZ35.SGD","IE0009355771.USD","BK4139","PRAX","LU0320765992.SGD","IE00BFTCPJ56.SGD","LU0109394709.USD","IE00BJT1NW94.SGD","LU0889565916.HKD","IE00B2B36J28.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2640962663","title":"Praxis Precision reports POWER1 study misses endpoint, pauses POWER2 enrollment","url":"https://stock-news.laohu8.com/highlight/detail?id=2640962663","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2640962663?lang=en_us&edition=fundamental","pubTime":"2026-06-02 04:27","pubTimestamp":1780345620,"startTime":"0","endTime":"0","summary":"Praxis Precision (PRAX) announced results from the Phase 2/3 POWER1 study evaluating vormatrigine in patients with focal onset seizures, or FOS. “W...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/praxis-precision-reports-power1-study-misses-endpoint-pauses-power2-enrollment-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/praxis-precision-reports-power1-study-misses-endpoint-pauses-power2-enrollment-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LU0109394709.USD","IE00BFTCPJ56.SGD","IE00B4R5TH58.HKD","IE0009355771.USD","LU0320765992.SGD","IE00BJJMRZ35.SGD","PRAX","IE00B2B36J28.USD","LU0889565916.HKD","IE0002141913.USD","IE00BJT1NW94.SGD","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2640964184","title":"Praxis says POWER1 trial of vormatrigine in focal seizures misses primary endpoint","url":"https://stock-news.laohu8.com/highlight/detail?id=2640964184","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2640964184?lang=en_us&edition=fundamental","pubTime":"2026-06-02 04:16","pubTimestamp":1780344974,"startTime":"0","endTime":"0","summary":"Praxis Precision Medicines reported Phase 2/3 POWER1 results for vormatrigine in highly refractory focal onset seizures.The study missed its main efficacy goal, raising uncertainty on the near-term development path for the program.A key secondary outcome showed a treatment signal, with stronger seizure control emerging later on the higher dose.Safety and tolerability supported continued dosing, with fewer than 10% discontinuing for adverse events.Enrollment in the ongoing POWER2 trial was paused to reassess the program and potential study changes.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260601:nNDLbTvrPV:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IE00BJT1NW94.SGD","IE00B2B36J28.USD","LU2210150020.SGD","LU0314104364.USD","SG9999014021.USD","NDAQ","LU2095319765.USD","SG9999014039.USD","IE00B64PRP62.GBP","IE00B3QW5Z07.USD","IE0002141913.USD","IE00BN0W2V16.EUR","IE00BN0W2W23.USD","LU0320765992.SGD","LU2210149790.SGD","IE00BJJMRZ35.SGD","BK4588","PRAX","BK4139","IE00BKPKM429.USD","IE0009355771.USD","LU0109394709.USD","SG9999014013.SGD","IE00B4R5TH58.HKD","SG9999014005.SGD","IE00BFTCPJ56.SGD","BK4585","IE00BGHQF748.EUR","IE00BN0W2T93.GBP","LU0889565916.HKD","BK4112"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2640964971","title":"Praxis Precision Medicines - 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Pauses Enrollment in Power2 Study to Reassess Vormatrigine Program","url":"https://stock-news.laohu8.com/highlight/detail?id=2640964970","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2640964970?lang=en_us&edition=fundamental","pubTime":"2026-06-02 04:15","pubTimestamp":1780344901,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260601:nTUA9ZKDHT:5","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["IE0009355771.USD","IE00B4R5TH58.HKD","LU0889565916.HKD","PRAX","BK4139","LU0320765992.SGD","IE00BJT1NW94.SGD","IE00BJJMRZ35.SGD","IE00BFTCPJ56.SGD","IE00B2B36J28.USD","LU0109394709.USD","IE0002141913.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2640964920","title":"Praxis Precision Medicines - Secondary 50% Response Rate Met; Seizure Reduction More Pronounced at 30 Mg Dose","url":"https://stock-news.laohu8.com/highlight/detail?id=2640964920","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2640964920?lang=en_us&edition=fundamental","pubTime":"2026-06-02 04:15","pubTimestamp":1780344901,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260601:nTUA9ZKDHT:3","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["IE00B2B36J28.USD","LU0889565916.HKD","IE00B4R5TH58.HKD","PRAX","IE0002141913.USD","IE0009355771.USD","IE00BJT1NW94.SGD","IE00BFTCPJ56.SGD","IE00BJJMRZ35.SGD","LU0320765992.SGD","LU0109394709.USD","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2640649799","title":"Praxis Precision Medicines Provides Vormatrigine Program Update","url":"https://stock-news.laohu8.com/highlight/detail?id=2640649799","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2640649799?lang=en_us&edition=fundamental","pubTime":"2026-06-02 04:15","pubTimestamp":1780344901,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260601:nTUA9ZKDHT:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["IE00B4R5TH58.HKD","PRAX","LU0109394709.USD","IE00BJJMRZ35.SGD","IE00BFTCPJ56.SGD","IE0009355771.USD","IE00B2B36J28.USD","BK4139","LU0889565916.HKD","IE00BJT1NW94.SGD","LU0320765992.SGD","IE0002141913.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2640649069","title":"Praxis Precision Medicines - 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