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Ionis Pharmaceuticals

59.88

-0.4800-0.80%

Post-market: 59.880.00000.00%19:30 EDT

Volume:1.87M

Turnover:112.59M

Market Cap:9.95B

PE:-17.21

High:60.99

Open:60.37

Low:59.78

Close:60.36

52wk High:86.74

52wk Low:49.13

Shares:166.18M

Float Shares:161.92M

Volume Ratio:0.93

T/O Rate:1.16%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-3.4800

EPS(LYR):-2.3812

ROE:-105.50%

ROA:-12.42%

PB:22.63

PE(LYR):-25.15

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Overview Company News Filings

Corrected-Ionis Pharmaceuticals Q1 Revenue USD 246 Million VS. Ibes Estimate USD 195.6 Million (Corrects Amount)

THOMSON REUTERS

Ionis partner GSK announces bepirovirsen NDA accepted for priority review

Ionis partner GSK’s bepirovirsen wins FDA Priority Review for hepatitis B NDA

Ionis Pharmaceuticals Inc: Pdufa Date of October 26, 2026

THOMSON REUTERS

Ionis Partner GSK Announces Bepirovirsen Accepted for Priority Review and Granted Breakthrough Therapy Designation by U.S. FDA as a Potential First-in-Class Medicine for Chronic Hepatitis B

THOMSON REUTERS

Ionis Pharmaceuticals price target lowered to $108 from $110 at TD Cowen

Earning Preview: Ionis Pharmaceuticals Q1 revenue is expected to increase by 56%, and institutional views are bullish

How Zilganersen’s Positive Pivotal Data and FDA Priority Review Could Impact Ionis Pharmaceuticals (IONS) Investors

Simply Wall St.

H.C. Wainwright Remains a Buy on Ionis Pharmaceuticals (IONS)

Ionis Pharmaceuticals Initiated at Buy by Canaccord Genuity

Ionis Pharmaceuticals price target raised to $130 from $95 at Morgan Stanley

Ionis Pharmaceuticals Is Maintained at Overweight by Morgan Stanley

This Pharma Stock Is Up 460% Over the Past Year. What Could Be Key to Future Gains. -- Barrons.com

Ionis announces additional results from zilganersen study in AxD

BRIEF-Ionis Pharmaceuticals Inc - Zilganersen 50 Mg Meets Primary Endpoint, Stabilizes Gait Speed In Patients ≥5 Years At Week 61

Canaccord Genuity Initiates Coverage on Ionis Pharmaceuticals With Buy Rating, $110 Price Target

MT Newswires Live

Ionis Pharmaceuticals Inc - Zilganersen Under FDA Priority Review With Pdufa Date Set for September 22, 2026

THOMSON REUTERS

Ionis Pharmaceuticals Inc - Key Secondary Endpoint Results Consistently Favored Zilganersen Over Control

THOMSON REUTERS

Ionis says zilganersen trial in Alexander disease meets primary endpoint on gait speed

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While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Ionis Pharmaceuticals Inc. published the original content used to generate this news brief via Business Wire  on April 28, 2026, and is solely responsible for the information contained therein.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260428:nNDL3N9n3Y:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"corporation","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2630969324","title":"Ionis Pharmaceuticals Inc: Pdufa Date of October 26, 2026","url":"https://stock-news.laohu8.com/highlight/detail?id=2630969324","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2630969324?lang=en_us&edition=fundamental","pubTime":"2026-04-28 14:06","pubTimestamp":1777356360,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260428:nTUA6B43VM:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2630324955","title":"Ionis Partner GSK Announces Bepirovirsen Accepted for Priority Review and Granted Breakthrough Therapy Designation by U.S. FDA as a Potential First-in-Class Medicine for Chronic Hepatitis B","url":"https://stock-news.laohu8.com/highlight/detail?id=2630324955","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2630324955?lang=en_us&edition=fundamental","pubTime":"2026-04-28 14:06","pubTimestamp":1777356360,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260428:nTUA6B43VM:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["IONS","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2629983480","title":"Ionis Pharmaceuticals price target lowered to $108 from $110 at TD Cowen","url":"https://stock-news.laohu8.com/highlight/detail?id=2629983480","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2629983480?lang=en_us&edition=fundamental","pubTime":"2026-04-23 20:40","pubTimestamp":1776948023,"startTime":"0","endTime":"0","summary":"TD Cowen lowered the firm’s price target on Ionis Pharmaceuticals (IONS) to $108 from $110 and keeps a Buy rating on the shares. The firm updated i...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/ionis-pharmaceuticals-price-target-lowered-to-108-from-110-at-td-cowen-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/ionis-pharmaceuticals-price-target-lowered-to-108-from-110-at-td-cowen-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["IONS","COWN","TD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1115572616","title":"Earning Preview: Ionis Pharmaceuticals Q1 revenue is expected to increase by 56%, and institutional views are bullish","url":"https://stock-news.laohu8.com/highlight/detail?id=1115572616","media":"Earnings Agent","labels":["earningPreview"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1115572616?lang=en_us&edition=fundamental","pubTime":"2026-04-23 08:24","pubTimestamp":1776903846,"startTime":"0","endTime":"0","summary":"Abstract Ionis Pharmaceuticals will release its first-quarter 2026 results on April 29, 2026, Pre-Market; this preview summarizes consensus revenue, earnings, and margin expectations for the quarter,...","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":"Earning Preview: Ionis Pharmaceuticals Q1 revenue is expected to increase by 56%, and institutional views are bullish","news_tag":"earningPreview","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2629024160","title":"How Zilganersen’s Positive Pivotal Data and FDA Priority Review Could Impact Ionis Pharmaceuticals (IONS) Investors","url":"https://stock-news.laohu8.com/highlight/detail?id=2629024160","media":"Simply Wall St.","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2629024160?lang=en_us&edition=fundamental","pubTime":"2026-04-23 02:05","pubTimestamp":1776881149,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals recently reported additional positive results from its pivotal Phase 1-3 trial of zilganersen in Alexander disease, showing statistically significant stabilization of gait speed and broad symptom benefits over 60 weeks, with the drug currently under FDA Priority Review and a PDUFA decision date set for September 22, 2026.\nBeyond motor endpoints, exploratory data showing reduced glial fibrillary acidic protein levels and consistently better patient- and...","market":"sg","thumbnail":"https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-ions/ionis-pharmaceuticals/news/how-zilganersens-positive-pivotal-data-and-fda-priority-revi","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-ions/ionis-pharmaceuticals/news/how-zilganersens-positive-pivotal-data-and-fda-priority-revi","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["BK4585","BK4588","LABU","BK4139","IONS","BK4211","ISBC"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2629274017","title":"H.C. Wainwright Remains a Buy on Ionis Pharmaceuticals (IONS)","url":"https://stock-news.laohu8.com/highlight/detail?id=2629274017","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2629274017?lang=en_us&edition=fundamental","pubTime":"2026-04-22 18:35","pubTimestamp":1776854139,"startTime":"0","endTime":"0","summary":"In a report released today, Mitchell Kapoor from H.C. Wainwright reiterated a Buy rating on Ionis Pharmaceuticals, with a price target of $120.00. ...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/h-c-wainwright-remains-a-buy-on-ionis-pharmaceuticals-ions-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/h-c-wainwright-remains-a-buy-on-ionis-pharmaceuticals-ions-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2629905508","title":"Ionis Pharmaceuticals Initiated at Buy by Canaccord Genuity","url":"https://stock-news.laohu8.com/highlight/detail?id=2629905508","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2629905508?lang=en_us&edition=fundamental","pubTime":"2026-04-21 23:58","pubTimestamp":1776787080,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/IONS/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  April 21, 2026 11:58 ET (15:58 GMT)","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2629055780","title":"Ionis Pharmaceuticals price target raised to $130 from $95 at Morgan Stanley","url":"https://stock-news.laohu8.com/highlight/detail?id=2629055780","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2629055780?lang=en_us&edition=fundamental","pubTime":"2026-04-21 23:57","pubTimestamp":1776787040,"startTime":"0","endTime":"0","summary":"Morgan Stanley raised the firm’s price target on Ionis Pharmaceuticals (IONS) to $130 from $95 and keeps an Overweight rating on the shares. The fi...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/ionis-pharmaceuticals-price-target-raised-to-130-from-95-at-morgan-stanley-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/ionis-pharmaceuticals-price-target-raised-to-130-from-95-at-morgan-stanley-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2629142055","title":"Ionis Pharmaceuticals Is Maintained at Overweight by Morgan Stanley","url":"https://stock-news.laohu8.com/highlight/detail?id=2629142055","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2629142055?lang=en_us&edition=fundamental","pubTime":"2026-04-21 23:55","pubTimestamp":1776786900,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/IONS/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  April 21, 2026 11:55 ET (15:55 GMT)","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2629037751","title":"This Pharma Stock Is Up 460% Over the Past Year. What Could Be Key to Future Gains. -- Barrons.com","url":"https://stock-news.laohu8.com/highlight/detail?id=2629037751","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2629037751?lang=en_us&edition=fundamental","pubTime":"2026-04-21 22:04","pubTimestamp":1776780240,"startTime":"0","endTime":"0","summary":"Shares of Arrowhead Pharmaceuticals have soared 460% over the past year, widely outpacing the broader market. Those gains could continue if a final handful of data points fall into place.Morgan Stanley analyst Michael Ulz is eagerly awaiting the release of Phase 3 study data in the third quarter, which he expects to \"unlock a multibillion-dollar opportunity that remains underappreciated.\". The vote of confidence came as Ulz upgraded Arrowhead stock to Overweight from Equal-weight on Tuesday with a $100 price target, up from $78. Shares advanced 5% to $72.72 on Tuesday.That commentary may seem ovrly upbeat, but Morgan Stanley isn't alone in singing Arrowhead's praises. It's among the 10 firms tracked by FactSet that rate the stock at Buy or the equivalent. Just two -- Leerink Partners and Bernstein Research -- rate it at Hold.This story may be one of direct market competition, but Ulz sees tremendous potential for the broad use of plozasiran, particularly among patients at high risk of ","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0267386448.USD","LU2271345857.HKD","LU0225283273.USD","LU2023251221.USD","IONS","LU2133065610.SGD","LU0971096721.USD","LU0070302665.USD","LU0208291251.USD","BK4534","LU0320765646.SGD","IE00BJJMRZ35.SGD","LU0158827781.USD","LU1732800096.USD","BK4127","LU0211331839.USD","LU1720051017.SGD","LU1989772840.SGD","IE00B4R5TH58.HKD","LU1244550221.USD","LU1720051108.HKD","LU1244550494.USD","BK4532","LU1791710582.SGD","LU2028103732.USD","LU2357305700.SGD","BK4007","BK4585","ARWR","LU0882574139.USD","IE00BKVL7J92.USD","LU1732799900.SGD","IE00BZ1G4Q59.USD","LU0106261372.USD","IE00B2B36J28.USD","LU2347655156.SGD","03165","RHHBY","LU1668664300.SGD","BK4588","LU0557290698.USD","LU0106831901.USD","LU1162221912.USD","NVS","LU1791710400.SGD","IE0009355771.USD","LU0795875169.SGD","LU0320765489.SGD","LU0314104364.USD","LU0912757837.SGD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2629303163","title":"Ionis announces additional results from zilganersen study in AxD","url":"https://stock-news.laohu8.com/highlight/detail?id=2629303163","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2629303163?lang=en_us&edition=fundamental","pubTime":"2026-04-21 20:39","pubTimestamp":1776775189,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals (IONS) announced additional results from the pivotal study of zilganersen in children and adults living with Alexander diseas...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/ionis-announces-additional-results-from-zilganersen-study-in-axd-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/ionis-announces-additional-results-from-zilganersen-study-in-axd-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2629036453","title":"BRIEF-Ionis Pharmaceuticals Inc - Zilganersen 50 Mg Meets Primary Endpoint, Stabilizes Gait Speed In Patients ≥5 Years At Week 61","url":"https://stock-news.laohu8.com/highlight/detail?id=2629036453","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2629036453?lang=en_us&edition=fundamental","pubTime":"2026-04-21 20:02","pubTimestamp":1776772932,"startTime":"0","endTime":"0","summary":"BRIEF-Ionis Pharmaceuticals Inc - Zilganersen 50 Mg Meets Primary Endpoint, Stabilizes Gait Speed In Patients ≥5 Years At Week 61April 21 (Reuters) - Ionis Pharmaceuticals Inc IONS.O:IONIS PHARMACEUTI","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260421:nFWN414025:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2629331340","title":"Canaccord Genuity Initiates Coverage on Ionis Pharmaceuticals With Buy Rating, $110 Price Target","url":"https://stock-news.laohu8.com/highlight/detail?id=2629331340","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2629331340?lang=en_us&edition=fundamental","pubTime":"2026-04-21 19:12","pubTimestamp":1776769967,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals (IONS) has an average rating of overweight and mean price target of $103.75, according to analysts polled by FactSet.(MT Newswires covers equity, commodity and economic research ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2629038004","title":"Ionis Pharmaceuticals Inc - Zilganersen Under FDA Priority Review With Pdufa Date Set for September 22, 2026","url":"https://stock-news.laohu8.com/highlight/detail?id=2629038004","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2629038004?lang=en_us&edition=fundamental","pubTime":"2026-04-21 19:02","pubTimestamp":1776769344,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260421:nFWN414025:3","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["IONS","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2629033857","title":"Ionis Pharmaceuticals Inc - Key Secondary Endpoint Results Consistently Favored Zilganersen Over Control","url":"https://stock-news.laohu8.com/highlight/detail?id=2629033857","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2629033857?lang=en_us&edition=fundamental","pubTime":"2026-04-21 19:02","pubTimestamp":1776769344,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260421:nFWN414025:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["IONS","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2629033826","title":"Ionis says zilganersen trial in Alexander disease meets primary endpoint on gait speed","url":"https://stock-news.laohu8.com/highlight/detail?id=2629033826","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2629033826?lang=en_us&edition=fundamental","pubTime":"2026-04-21 19:01","pubTimestamp":1776769276,"startTime":"0","endTime":"0","summary":"Ionis highlighted additional positive data from pivotal zilganersen study in Alexander disease, scheduled for presentation at AAN 2026 annual meeting.Trial results showed treatment stabilized walking ability in patients age 5 and older versus control.Data also indicated improved gross motor function in children age 2 to 4 versus control.Patient- and clinician-reported assessments broadly favored zilganersen, supporting potential benefit across multiple symptoms.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Ionis Pharmaceuticals Inc. published the original content used to generate this news brief via Business Wire  on April 21, 2026, and is solely responsible for the information contained therein.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260421:nNDL7JYS6N:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","IONS"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":10,"pageCount":10,"totalSize":199,"code":"91000000","status":"200"}]}}